Johan Hagelbäck; Kenny Svensson MCS-2003:07/MSE-2003:10, pp. 26. Inst. för programvaruteknik och datavetenskap/Dept. of Software Engineering and Computer Science, 2003.
We have developed a new approach for locating transmembrane domains in protein sequences based on hydrophobicity analysis and backpropagation neural network or k-nearest-neighbor as classifiers. Our system was able to locate over 98% of the transmembrane domains and the total accuracy including overpredictions was above 95%.