Re-osseointegration on previously contaminated surfaces: a systematic review

Document type: Conference Papers
Peer reviewed: Yes
Author(s): Stefan Renvert, Ioannis Polyzois, Rory Maguire
Title: Re-osseointegration on previously contaminated surfaces: a systematic review
Conference name: 2nd EAO Consensus Conference 2009
Year: 2009
Pagination: 216-227
Publisher: Wiley Blackwell
City: Pfaffikon, SWITZERLAND
URI/DOI: 10.1111/j.1600-0501.2009.01786.x
ISI number: 000268296200020
Organization: Blekinge Institute of Technology
Department: School of Health Science (Sektionen för hälsa)
School of Health Science S-371 79 Karlskrona
+46 455 38 50 00
Language: English
Abstract: The aim of this review was to search the literature for the existing evidence of re-osseointegration after treatment of peri-implantitis at contaminated implant surfaces.

Material and Methods

A search of PubMed as well as additional hand search of articles were conducted. Publications and articles accepted for publication up to November 2008 were included.


A total of 25 animal studies fulfilled the inclusion criteria for this review. Access surgery with closed healing has been observed to positively influence the rate of re-osseointegration when compared with non-surgical decontamination of the implant surface with open healing. Open debridement including surface decontamination may result in re-osseointegration and this integration was more pronounced on rougher than on smooth implant surfaces. The adjunctive use of regenerative procedures resulted in varying amounts of re-osseointegration.


Re-osseointegration is possible to obtain on a previously contaminated implant surface and can occur in experimentally induced peri-implantitis defects following therapy. The amount of re-osseointegration, varied considerably within and between studies. Implant surface characteristics may influence the degree of re-osseointegration. Surface decontamination alone can not achieve substantial re-osseointegration on a previously contaminated implant surface. No method predictably accomplished complete resolution of the peri-implant defect.
Subject: Medical Sciences
Keywords: animal studies, healing, peri-implantitis, re-osseointegration, treatment