Systemic antibiotics and debridement of peri-implant mucositis. A randomized clinical trial
| Document type: | Journal Articles |
|---|---|
| Article type: | Original article |
| Peer reviewed: | Yes |
| Author(s): | Hadar Hallström, Rutger Persson, Susann Lindgren, Maria Olofsson, Stefan Renvert |
| Title: | Systemic antibiotics and debridement of peri-implant mucositis. A randomized clinical trial |
| Journal: | Journal of Clinical Periodontology |
| Year: | 2012 |
| Volume: | 39 |
| Issue: | 6 |
| Pagination: | 574-581 |
| ISSN: | 0303-6979 |
| Publisher: | Wiley Blackwell |
| URI/DOI: | 10.1111/j.1600-051X.2012.01884.x |
| ISI number: | 000303855200009 |
| Organization: | Blekinge Institute of Technology |
| Department: | School of Health Science (Sektionen för hälsa) School of Health Science S-371 79 Karlskrona +46 455 38 50 00 http://www.bth.se/hal/ |
| Language: | English |
| Abstract: | Background This RCT compared non-surgical treatment of peri-implant mucositis with or without systemic antibiotics. Materials and Methods Forty-eight subjects received non-surgical debridement with or without systemic Azithromax (R) (4 similar to days), and were followed during 6 similar to months. The checkerboard DNA-DNA hybridization method was used to analyse the microbiological material. Results Five subjects were excluded due to antibiotic medication during follow-up. At baseline,1 and 3 similar to months no group differences were found. Statistical analysis failed to demonstrate differences in probing pocket depths (PPD) values at 6 similar to months (Mean diff PPD: 0.5 similar to mm, SE: +/- 0.4 similar to mm, 95% CI: -0.2, 1.3, p similar to 0.16). Mean% implant bleeding decreased between baseline and month 6 from 82.6% to 27.3% in the test, and from 80.0% to 47.5% in the control group (p similar to 0.02). Throughout the study, no study group differences in bacterial counts were found. Conclusion No short-term differences were found between study groups. The clinical improvements observed at 6 similar to months may be attributed to improvements in oral hygiene. The present study does not provide evidence for the use of systemic antibiotics in treatment of peri-implant mucositis. |
| Subject: | Medical Sciences |
| Keywords: | antibiotics, microbiology, peri-implant disease, peri-implant mucositis, therapy |
